Fetal blood is slightly more acidic (pH 7.3) than maternal blood. Q: Lidocaine is a weak base; how would this characteristic affect drug absorption and fetal exposure to this drug during gestation?

Answer: Lidocaine would accumulate in the fetus and potentially become toxic.

Second question: Now what would happen if drug that is given is a weak acid? (Professor says this will be an essay question so you must understand it. :2in1: )


I sort of understand why the base would accumulate.
Can someone explain what would happen if a weak acid is given??