Had a patient in the PACU the other day with PONV. No IV (lost in the PACU post-op), unable to gain access, pt. otherwise stable, ASA I having day surgery.

Attending suggests IM ephedrine (pt. feels better before drug is given), when I asked the MDA if, in his experience, ephedrine was helpful in treating PONV, he told that ephedrine only helps with PONV if the reason for the PONV is low BP.

However, I have since read (in M&M) that ephedrine is thought to have antiemetic properties. So, I was just looking for any research on the effectiveness/mechanism by which ephedrine may help prevent or treat PONV.

Of course, I would also be interested in personal experiences and (of course doses). Thanks!