Regarding drug metabolism by cytochrome P450 isoenzymes:

a) cytochrome P450 makes up 1% of total liver proteins
b) the most important enzyme is CYP3A4
c) the system is responsible for most of the reductive metabolism in humans
d) volatile anesthetics are metabolized by CYP2E1
e) some isoenzymes are inhibited strongly by erythromycin

Answer T or F for each please!