A 45-year-old man diagnosed with a large mediastinal lymphoma was started on an appropriate chemotherapy regimen including cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP). On the second day of treatment, dysrhythmias are noticed on EKG. Laboratory studies review: phosphorus 5.2 mg/dl, potassium 6.3 mg/dl, corrected calcium 6.7 mg/dl, uric acid 8.9 mg/dl and creatinine 1.6 mg/dl. Which of the following is the MOST appropriate treatment?


A) IV hydration, phosphate binders and alkalinization of urine
B) IV hydration, rasburicase, calcium gluconate, potassium exchange resin
C) IV hydration, allopurinol, calcium gluconate, potassium exchange resin
D) IV hydration, potassium exchange resin, phosphate binders