TRUE statements concerning the trx of metabolic acidosis with bicarb include:

1. it consistently improves intracell pH.

2. it is clearly effective in improving outcome.

3. the appropriate dose is 0.7 x (body weight in kg) x (24 - HCO3).

4. it can increase PaCO2.

A. 1, 2, and 3 correct
B. 1 and 3 correct
C. 4 correct
D. All correct